This unit will enable students to understand and evaluate research and literature in the neurobiology of dementia, and to use and communicate that knowledge in their own personal context. It covers the major elements of the brain and the functions of nerve and glial cells, including neurotransmission, in order to support the understanding of the degenerative processes of dementing diseases, the relationship between genetics, pathology, degeneration, biomarkers and diagnosis, and the basis of therapeutics which affect the central nervous system. A section on the neurophysiology of pain, a significant issue in dementia care, is included. This unit of study is part of the Postgraduate Studies in Dementia Program, offered by the University of Tasmania.